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Managing Impurities in GLP‑1 Peptides: How Carbon Media Enhances Purification
Crude GLP-1–class peptides and other long sequences typically enter purification at 45–65% area purity. The dominant impurities present...
Sep 22


Benchmarking All‑Carbon Microbeads for Peptide Chromatography: Tested with Diabetes and Weight‑Loss Peptides
Peer‑reviewed in ACS Omega : Matches silica C18 on efficiency, LOD/LOQ, and loading, with stable performance at high pH and 100% aqueous...
Aug 12


Separation and Purification of Sovateltide Using NanoPak-C All Carbon Microbeads
We have released an application note that provides a strong and scalable approach for the purification Figure. Chemical structure...
Jun 17


How Millennial Scientific is Tackling PFAS Challenges
Per- and polyfluorinated alkyl substances (PFAS) are synthetic chemicals widely used in industrial processes and consumer products. ...
May 16


Extending the Lifetime of Your Reverse Phase Columns: Cleaning and Regeneration Techniques
This blog provides an overview of column cleaning and regeneration techniques to extend the lifetime of reverse-phase HPLC columns.
Apr 3


Extending HPLC Column Lifetimes: Causes of Column Contamination
This blog, part of our two-part series on extending the lifetime of HPLC Columns, explores the probable causes of column contamination.
Apr 1


Millennial Scientific partners with Leach Particle Technologies for recycling All Carbon Chromatography Media
Millennial Scientific and Leach Particle Technologies partner to minimize, reuse, and recycle NanoPak-C All Carbon chromatography media.
Mar 17


Understanding Pharmaceutical Purity, Assay, and Potency Assessment Through Liquid Chromatography
A pharmaceutical's purity, assay, and potency are terms commonly used when discussing drug quality testing. Due to its accuracy and...
Mar 2


The End-Of-Life Management of Si-C18 and NanoPak-C All Carbon Chromatography Media
End-of-life waste management of chromatography operations includes the disposal of the stationary phase media and solvents (water and...
Feb 6


Milestone Alert: NanoPak-C Analytical Grade Media Successfully Passes Beta Testing Milestone
Millennial Scientific is pleased to announce a major achievement in our product development: the successful completion of the beta...
Sep 20, 2024


Chinese Patent Office Issues Notice of Allowance for Millennial Scientific’s Technology
Millennial Scientific is pleased to report that the Chinese Patent Office has issued the Company a Notice of Allowance concerning its...
Sep 17, 2024


Role of Flash Chromatography in Peptide Purification
Flash chromatography is a valuable tool in peptide purification workflows, especially as a pre-purification or cleanup step.
Sep 13, 2024


Understanding Peptide and Protein Aggregation: A Guide to Terminologies, Implications, Factors, and the Role of Liquid Chromatography
The aggregation or clumping of peptides and proteins is a crucial phenomenon in biology , influenced by various factors [1]....
Jul 29, 2024


Analyzing Bovine Serum Albumin (BSA) with NanoPak-C All Carbon HPLC Columns
NanoPak-C All Carbon media has adjustable pore size and surface area that is suitable for separating proteins in reverse phase. We demonstra
Jul 12, 2024


Understanding Ozempic, Wegovy, and Other GLP-1 Therapeutic Peptides: Background, Composition, and Manufacturing
Image adapted from [1]. Ozempic, Weight Loss, and GLP-1 Therapy Ozempic is a once-weekly injection first approved by the Food and Drug...
Jul 5, 2024


Simultaneous Determination of Insulin Aspart and its Phenolic Preservatives Using NanoPak-C All Carbon HPLC Columns
We have published an application note that presents a reliable and quick method using NanoPak- C All carbon columns for simultaneously...
Jun 26, 2024


Separation of Semaglutide and Liraglutide: An Optimized Method Using NanoPak-C All Carbon Microbeads
We have published an application note that presents an optimized method for HPLC separation of semaglutide and liraglutide. This method...
Jun 5, 2024


How Does Peptide Manufacturing Affect the Environment?
Peptides are considered “medium molecules.” They typically consist of 2-50 amino acids, and their size is measured in molecular weights...
May 24, 2024


Demystifying Oligonucleotide Separation
Oligonucleotides are tiny fragments of DNA or RNA. Our genetic information is stored in DNA and RNA. These molecules are also known as...
May 1, 2024


Carbon’s role in Reversed-Phase Liquid Chromatography Retention and Selectivity
The Basics The most widely used mode of chromatography is Reversed-Phase Liquid Chromatography (RPLC). Accounting for more than 90% of...
Mar 22, 2024
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