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Where NanoPak C All-Carbon Capillary HPLC Columns Fit in Bottom-Up Proteomics
NanoPak-C All-Carbon capillary HPLC columns offer porous graphitic carbon selectivity for glycans, glycopeptides, PTM-rich peptides, and polar metabolites in nanoLC–MS proteomics workflows. In an independent head-to-head comparison with commercial PGC and C18, NanoPak-C showed sharper peaks, faster column stabilization, and a cleaner MS baseline. Read our technical note and blog to learn where all-carbon media fits in bottom-up proteomics.
3 days ago


Advancing Next‑Generation Chromatography with Support from New York State
Millennial Scientific is advancing NanoPak‑C, a 3D‑printed monolith platform designed to improve biologics chromatography. Supported by an NIH SBIR Phase I project and Empire State Development’s NYSTAR Innovation Matching Grants Program, this work helps bridge the gap between R&D and commercialization, enabling scalable, customizable separation media for more efficient bioprocessing.
Apr 15


Millennial Scientific Invited to Pitch at BioTools Innovator 2026 Road Tour
Millennial Scientific, selected among the top 15% of 500+ global applicants for the BioTools Innovator 2026 Road Tour, develops custom chromatography media and bioprocess materials for next-generation biologics manufacturing. Our advanced separation technologies support the purification and processing of peptides, large proteins, nucleic acids, and cells — enabling faster, more efficient manufacturing for the life science tools and biopharmaceutical industries.
Mar 17


Product Milestone: NanoPak‑C 3D‑Printed Monoliths for Biologics Chromatography
NanoPak‑C is our new class of 3D‑printed carbon monoliths designed for miniaturized biologics chromatography. Built from proprietary all‑carbon microbeads, these microstructured devices retain a microwell‑plate format while enabling high‑performance solid‑phase extraction and chromatography of proteins and other complex biologics from ultra‑low‑volume samples.
Mar 12


United States Patent Office Issues Notice of Allowance for Millennial Scientific’s Microdroplet‑Based Materials Manufacturing Platform
Millennial Scientific is pleased to announce that the United States Patent and Trademark Office (USPTO) has issued a Notice of Allowance for U.S. patent application No. 17/760,477, titled “A Process for Synthesis of Carbon Beads.” This application is a U.S. National Stage filing under 35 U.S.C. 371 and corresponds to Millennial Scientific’s core microdroplet-based manufacturing process for all‑carbon and other types of custom microbeads.
Feb 17


Millennial Scientific End Of Year Review 2025
In 2025, Millennial Scientific made substantial progress. We introduced new products, advanced our sustainability efforts, and expanded our technical capabilities. Below is our End-of-Year Review. New product innovations: We launched two major product lines for biologic purification: NanoPak-C All Carbon Perfusion Microbeads and scalable, custom NanoPak-C Monolith Media . These products improve purification efficiency for large biologics, including protein complexes, exosome
Jan 1


Benchmarking All‑Carbon Microbeads for Peptide Chromatography: Tested with Diabetes and Weight‑Loss Peptides
Peer‑reviewed in ACS Omega : Matches silica C18 on efficiency, LOD/LOQ, and loading, with stable performance at high pH and 100% aqueous...
Aug 12, 2025


Scalable Custom NanoPak-C Monolith Media for Improved Biologic Purification
Millennial Scientific has expanded its manufacturing capabilities to produce scalable custom 3D monolith Figure 1. Digital images of...
Jul 29, 2025


Advancing Biologic Purification: Introducing NanoPak-C All Carbon Perfusion Microbeads
Millennial Scientific has developed a suite of novel NanoPak-C All Carbon perfusion microbeads, designed for the purification of...
Jul 17, 2025


Separation and Purification of Sovateltide Using NanoPak-C All Carbon Microbeads
We have released an application note that provides a strong and scalable approach for the purification Figure. Chemical structure...
Jun 17, 2025


Millennial Scientific partners with Leach Particle Technologies for recycling All Carbon Chromatography Media
Millennial Scientific and Leach Particle Technologies partner to minimize, reuse, and recycle NanoPak-C All Carbon chromatography media.
Mar 17, 2025


Millennial Scientific Recognized as A Deeptech Pioneer by Hello Tomorrow
Millennial Scientific is honored to be selected as Hello Tomorrow’s Deep Tech Pioneers in the lead-up to
their Global Challenge and Summit.
Nov 17, 2024


Milestone Alert: NanoPak-C Analytical Grade Media Successfully Passes Beta Testing Milestone
Millennial Scientific is pleased to announce a major achievement in our product development: the successful completion of the beta...
Sep 20, 2024


Chinese Patent Office Issues Notice of Allowance for Millennial Scientific’s Technology
Millennial Scientific is pleased to report that the Chinese Patent Office has issued the Company a Notice of Allowance concerning its...
Sep 17, 2024


Millennial Scientific Signs Distribution Agreement with Leach Particles Technologies
Millennial Scientific signs a distribution agreement with Leach Particle Technologies to serve our customers in the United Kingdom & Europe.
Aug 26, 2024


Millennial Scientific Announces Japanese Patent on Microbead Synthesis Technology
Millennial Scientific is pleased to announce that it has received a Notice of Allowance from the Japanese Patent Office for its patent...
Mar 7, 2024


NanoPak-C All Carbon HPLC Capillary Columns for Proteomics & Other Biologics
Millennial Scientific is pleased to introduce NanoPak-C All Carbon capillary columns (less than 500 µm internal diameter (ID)) for...
Feb 16, 2024


Millennial Scientific to Present & Exhibit at The Advances in Proteomics Conference
Millennial Scientific will exhibit it's portfolio of Proteomics sample processing and chromatography products at the Advances in...
Feb 13, 2024


Scientific American Highlights All Carbon Microbead Technology
Scientific American highlighted our core microfluidics microdroplet-based flow chemistry technology. The article distills the...
Feb 5, 2024


Introducing Reverse Phase Flash Media & Columns
Millennial Scientific Launches All Carbon Reverse Phase Flash Media & Columns. Features include: • Spherical mechanically robust graphite...
Jan 31, 2024
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