Millennial Scientific will exhibit it's portfolio of Proteomics sample processing and chromatography products at the Advances in Proteomics Technologies (APT-2024) International Conference and workshop to be held at IIT, Mumbai from 17th to 20th February 2024.
The conference and worshops aim to provide participants with insights into the recent advances in the field of proteomics.
Dr. Balaji Sitharaman, President of Millennial Scientific will present a talk titled ‘Electrochemically Modulated Liquid Chromatography - Implications for Proteomics’
Solid phase extraction and liquid chromatography separation are widely employed in processing protein
samples. Herein, we present the synthesis, characterization, and proteomics applications of
electrochemically modulated liquid chromatography (EMLC) stationary phase material. An externally
applied (Ea) voltage (≤2Volts) tweaks the electrically- conductive all-carbon spherical microparticles
stationary phase material's interfacial properties (e.g., surface charge and oxidation state). This capability
theoretically allows the stationary Phase's composition to be tuned before, during, and after the
separation procedure. The capture and release of charged analytes driven by applied voltage simplifies
workflow. It lowers the use of ionic buffers for retention and release of the analytes from the stationary
phase material and reduces operational and maintenance costs. The pseudo-capacitive behavior of the
microbeads allows for charge storage and holds compounds with surface charges even after removing
the voltage, allowing wash procedures. The tunable size (diameter 5 µm to ≥ 1 mm) and porosity (pore
size 10 -100 nm) enable efficient, repetitive, selective separation of charged small (e.g., monophosphate
nucleotides, peptides) and large (DNA, RNA, charged proteins) analytes. The ion exchange and reverse-
phase separation mechanisms allow multimodal separation of analytes.
Exhibition details:
Date: 17th - 20th Feb 2024
Time: 10AM - 6PM
Venue: Victor Menezes Convention Centre (VMCC), IIT Bombay
Talk details
Lecture 7 : Electrochemically Modulated Liquid Chromatography - Implications for
Proteomics by Dr.Balaji Sitharaman
Date: 18th Feb 2024, Sunday
Time: 10:30 - 11:00 AM
Venue: Room 3, VMCC, IIT Bombay
For more information on proteomics sample processing and chromatography products, or to request samples, please email us at inquiry@millennialscientific.com, call us at 855 388 2800 or fill in our online form.