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Simplifying RNA QC: Can Carbon-Based Digital Liquid Chromatography Help?
RNA therapeutics require characterization of up to 20 critical quality attributes, which currently demands multiple dedicated LC methods — reversed-phase, anion-exchange, and size-exclusion — on separate instruments. Carbon-based digital liquid chromatography offers a different direction. By applying voltage to an all-carbon conductive stationary phase, retention can be tuned in real time. We explore how this approach may consolidate RNA QC workflows into a single compact pla
2 days ago


Digital Liquid Chromatography with All‑Carbon Microbeads: Applications in Sample Cleanup, PFAS, Multi‑Omics, and RNA QC
Electrochemically modulated liquid chromatography (EMLC), also called digital liquid chromatography, uses applied voltage to dynamically tune analyte retention on all-carbon microbeads. This voltage-tunable platform enables smarter sample cleanup, selective PFAS capture, streamlined multi-omics workflows, and RNA critical quality attribute testing. All on one conductive stationary phase. Explore how Millennial Scientific's all-carbon EMLC platform is advancing separations acr
3 days ago


How are Carbon Microbeads Facilitating Electrochemically Modulated Liquid Chromatography of Charged Molecules?
Charged molecules are everywhere — from DNA therapeutics to environmental toxins. Yet separating and analyzing them cleanly remains one of analytical chemistry's toughest challenges. Traditional methods like IP-RPLC and IEX force a frustrating trade-off: great separation or great MS detection, never both. Electrochemically Modulated Liquid Chromatography (EMLC) using carbon microbeads, replaces messy chemicals with precise electrical control for cleaner, faster, and more sust
Apr 8


Demystifying Oligonucleotide Separation
Oligonucleotides are tiny fragments of DNA or RNA. Our genetic information is stored in DNA and RNA. These molecules are also known as...
May 1, 2024
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