NanoPak-C All-Carbon capillary HPLC columns offer porous graphitic carbon selectivity for glycans, glycopeptides, PTM-rich peptides, and polar metabolites in nanoLC–MS proteomics workflows. In an independent head-to-head comparison with commercial PGC and C18, NanoPak-C showed sharper peaks, faster column stabilization, and a cleaner MS baseline. Read our technical note and blog to learn where all-carbon media fits in bottom-up proteomics.

Proteomics labs increasingly push LC–MS systems to their limits, yet sample prep is often constrained by media that are suboptimal for today’s harsh conditions, complex matrices, or high-sensitivity PTM analysis All‑carbon microbeads with tunable pore size and surface chemistry offer a way to decouple capacity from “stickiness” so you can match the bead to the biology, not the other way around.