High-temperature HPLC improves mass transfer, reduces retention times, and controls difficult analyte behavior — but only if the stationary phase can handle the heat. NanoPak-C All-Carbon columns, based on porous graphitic carbon media, are evaluated for demanding reversed-phase workflows from cyclosporine analysis at 80 °C to illicit drug salt identification and oligonucleotide separations. Learn how all-carbon media can support robust, repeatable high-temperature LC methods

Millennial Scientific is advancing NanoPak‑C, a 3D‑printed monolith platform designed to improve biologics chromatography. Supported by an NIH SBIR Phase I project and Empire State Development’s NYSTAR Innovation Matching Grants Program, this work helps bridge the gap between R&D and commercialization, enabling scalable, customizable separation media for more efficient bioprocessing.

Crude GLP-1–class peptides and other long sequences typically enter purification at 45–65% area purity. The dominant impurities present...

Millennial Scientific has expanded its manufacturing capabilities to produce scalable custom 3D monolith Figure 1. Digital images of...

This blog is part of our separation science primer series which provides an easy-to-understand overview of key topics in solid-phase...