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Managing Impurities in GLP‑1 Peptides: How Carbon Media Enhances Purification
Crude GLP-1–class peptides and other long sequences typically enter purification at 45–65% area purity. The dominant impurities present...
Sep 22


Benchmarking All‑Carbon Microbeads for Peptide Chromatography: Tested with Diabetes and Weight‑Loss Peptides
Peer‑reviewed in ACS Omega : Matches silica C18 on efficiency, LOD/LOQ, and loading, with stable performance at high pH and 100% aqueous...
Aug 12


The Impact of Composition, Aggregation, and Solubility on Glucagon-like peptide-1 Purification
pH-dependent aggregation behavior of peptides. In a previous blog post, we delved into the complex issue of peptide and protein...
Aug 1, 2024


Understanding Ozempic, Wegovy, and Other GLP-1 Therapeutic Peptides: Background, Composition, and Manufacturing
Image adapted from [1]. Ozempic, Weight Loss, and GLP-1 Therapy Ozempic is a once-weekly injection first approved by the Food and Drug...
Jul 5, 2024


Separation of Semaglutide and Liraglutide: An Optimized Method Using NanoPak-C All Carbon Microbeads
We have published an application note that presents an optimized method for HPLC separation of semaglutide and liraglutide. This method...
Jun 5, 2024
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