A novel isoelectric focusing (IEF) platform for low‑input proteomics, using 3D‑printed immobilized pH gradient (IPG) carbon microbead arrays for first‑dimension prefractionation. NanoPak‑C‑IPG enables localized pI‑based protein focusing, high extraction efficiency, and direct hand‑off to all‑carbon NanoPak‑C RP‑HPLC, addressing key limitations of conventional IPG strips in single‑cell and low‑sample workflows.

Millennial Scientific is advancing NanoPak‑C, a 3D‑printed monolith platform designed to improve biologics chromatography. Supported by an NIH SBIR Phase I project and Empire State Development’s NYSTAR Innovation Matching Grants Program, this work helps bridge the gap between R&D and commercialization, enabling scalable, customizable separation media for more efficient bioprocessing.

Millennial Scientific, selected among the top 15% of 500+ global applicants for the BioTools Innovator 2026 Road Tour, develops custom chromatography media and bioprocess materials for next-generation biologics manufacturing. Our advanced separation technologies support the purification and processing of peptides, large proteins, nucleic acids, and cells — enabling faster, more efficient manufacturing for the life science tools and biopharmaceutical industries.